There are some extra things you can do if you enable the debug keys.
To do so, add this key your user_settings.json at the same level than your "user_id" (make sure to add commas where needed):
"enable_debug_keys" : true
You will see more options in the Controls tab of the in-game Settings under the "Debug" group. Some of them will allow you to customize the hotkeys for the default console and the Lua console.
The most common used ones are:
Save & Reload - performs a "Quick Save" + "Quick Load"
Switch Debug Shapes View - toggles between 3 states: showing the collision and other regions of the selected entity, showing the regions for all the entities in the world, and not showing anything.
Show Terrain Coordinates - toggles showing the terrain coordinates next to the cursor.
Show Rendering Stats - shows the FPS and other rendering stats while pressed.
The rest of Debug options are different debug views and the like.